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Design, Synthesis, Characterization, and Crystal Structure Studies of Nrf2 Modulators for Inhibiting Cancer Cell Growth In Vitro and In Vivo

[Image: see text] Nrf2 is one of the important therapeutic targets studied extensively in several cancers including the carcinomas of the colon and rectum. However, to date, not many Nrf2 inhibitors showed promising results for retarding the growth of colorectal cancers (CRCs). Therefore, in this st...

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Detalles Bibliográficos
Autores principales: Chikkegowda, Prathima, Pookunoth, Baburajeev C., Bovilla, Venugopal R., Veeresh, Prashanthkumar M., Leihang, Zonunsiami, Thippeswamy, Thippeswamy, Padukudru, Mahesh A., Hathur, Basavanagowdappa, Kanchugarakoppal, Rangappa S., Basappa, Madhunapantula, SubbaRao V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153663/
https://www.ncbi.nlm.nih.gov/pubmed/34056161
http://dx.doi.org/10.1021/acsomega.0c06345