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Identification of Potential Pathogenic Super-Enhancers-Driven Genes in Pulmonary Fibrosis

Abnormal fibroblast differentiation into myofibroblast is a crucial pathological mechanism of pulmonary fibrosis (PF). Super-enhancers, a newly discovered cluster of regulatory elements, are regarded as the regulators of cell identity. We speculate that abnormal activation of super-enhancers must be...

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Detalles Bibliográficos
Autores principales: Li, Hang, Zhao, Caiping, Li, Zeli, Yao, Kainan, Zhang, Jingjing, Si, Wenwen, Liu, Xiaohong, Jiang, Yong, Zhu, Meiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153712/
https://www.ncbi.nlm.nih.gov/pubmed/34054916
http://dx.doi.org/10.3389/fgene.2021.644143