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Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, and Reemergence of Pertussis

Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and potential return of what was once the major kille...

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Detalles Bibliográficos
Autores principales: Ma, Longhuan, Caulfield, Amanda, Dewan, Kalyan K., Harvill, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153889/
https://www.ncbi.nlm.nih.gov/pubmed/34014152
http://dx.doi.org/10.3201/eid2706.203850