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Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation

[Image: see text] The Chikungunya virus (CHIKV) is an arbovirus belonging to the genus Alphavirus of the Togaviridae family. CHIKV is transmitted by the mosquitoes and causes Chikungunya fever. CHIKV outbreaks have occurred in Africa, Asia, Europe, and the countries of Indian and Pacific Oceans. In...

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Detalles Bibliográficos
Autores principales: Ivanova, Larisa, Rausalu, Kai, Ošeka, Maksim, Kananovich, Dzmitry G., Žusinaite, Eva, Tammiku-Taul, Jaana, Lopp, Margus, Merits, Andres, Karelson, Mati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153904/
https://www.ncbi.nlm.nih.gov/pubmed/34056242
http://dx.doi.org/10.1021/acsomega.1c00625