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Discovery of Novel CCR5 Ligands as Anticolorectal Cancer Agents by Sequential Virtual Screening

[Image: see text] C-C chemokine receptor type 5 (CCR5) is a member of the G protein-coupled receptor. CCR5 and its interaction with chemokine ligands have been crucial for understanding and tackling human immunodeficiency virus (HIV)-1 entry into target cells. In recent years, the change in CCR5 exp...

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Detalles Bibliográficos
Autores principales: El-Zohairy, Mariam A., Zlotos, Darius P., Berger, Martin R., Adwan, Hassan H., Mandour, Yasmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153923/
https://www.ncbi.nlm.nih.gov/pubmed/34056245
http://dx.doi.org/10.1021/acsomega.1c00681