Development of a Sensitive Headspace Gas Chromatography–Mass Spectrometry Method for the Simultaneous Determination of Nitrosamines in Losartan Active Pharmaceutical Ingredients

[Image: see text] Nitrosamine impurities in angiotensin II receptor antagonists (sartans) containing a tetrazole group represent an urgent concern for active pharmaceutical ingredient (API) manufacturers and global regulators. Regarding safety, API manufacturers must develop methods to monitor the l...

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Detalles Bibliográficos
Autores principales: Wichitnithad, Wisut, Sudtanon, Orawan, Srisunak, Pawadee, Cheewatanakornkool, Kamonrak, Nantaphol, Siriwan, Rojsitthisak, Pornchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153937/
https://www.ncbi.nlm.nih.gov/pubmed/34056258
http://dx.doi.org/10.1021/acsomega.1c00982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153937/
https://www.ncbi.nlm.nih.gov/pubmed/34056258
http://dx.doi.org/10.1021/acsomega.1c00982

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