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Contribution of dsRBD2 to PKR Activation

[Image: see text] Protein kinase R (PKR) is a key pattern recognition receptor of the innate immune pathway. PKR is activated by double-stranded RNA (dsRNA) that is often produced during viral genome replication and transcription. PKR contains two tandem double-stranded RNA binding domains at the N-...

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Detalles Bibliográficos
Autores principales: Hesler, Stephen, Angeliadis, Matthew, Husain, Bushra, Cole, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153938/
https://www.ncbi.nlm.nih.gov/pubmed/34056292
http://dx.doi.org/10.1021/acsomega.1c00343