Cargando…

Dasatinib–SIK2 Binding Elucidated by Homology Modeling, Molecular Docking, and Dynamics Simulations

[Image: see text] Salt-inducible kinases (SIKs) are calcium/calmodulin-dependent protein kinase (CAMK)-like (CAMKL) family members implicated in insulin signal transduction, metabolic regulation, inflammatory response, and other processes. Here, we focused on SIK2, which is a target of the Food and...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Mingsong, Wang, Lun, Li, Penghui, Liu, Jiang, Chen, Lijuan, Xu, Dingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8153941/
https://www.ncbi.nlm.nih.gov/pubmed/34056256
http://dx.doi.org/10.1021/acsomega.1c00947