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Synthesis, Hemolytic Studies, and In Silico Modeling of Novel Acefylline–1,2,4-Triazole Hybrids as Potential Anti-cancer Agents against MCF-7 and A549

[Image: see text] A series of novel theophylline-7-acetic acid (acefylline)-derived 1,2,4-triazole hybrids with N-phenyl acetamide moieties (11a–j) have been synthesized and tested for their inhibitory (in vitro) potential against two cancer cell lines, A549 (lung) and MCF-7 (breast), using MTT assa...

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Detalles Bibliográficos
Autores principales: Shahzadi, Irum, Zahoor, Ameer Fawad, Rasul, Azhar, Mansha, Asim, Ahmad, Sajjad, Raza, Zohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154016/
https://www.ncbi.nlm.nih.gov/pubmed/34056349
http://dx.doi.org/10.1021/acsomega.1c00424