Effect of High-Energy Milling on the Dissolution of Anti-HIV Drug Efavirenz in Different Solvents

[Image: see text] The anti-HIV drug efavirenz (EFV) displays low and variable bioavailability because of its poor aqueous solubility. Ball milling is a simple and cost-effective alternative to traditional micronization to improve the solubility and dissolution rate of EFV. A multibody dynamics model...

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Detalles Bibliográficos
Autores principales: Ataollahi, Narges, Broseghini, Marica, Ferreira, Fabio F., Susana, Alberto, Pizzato, Massimo, Scardi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154137/
https://www.ncbi.nlm.nih.gov/pubmed/34056416
http://dx.doi.org/10.1021/acsomega.1c00712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154137/
https://www.ncbi.nlm.nih.gov/pubmed/34056416
http://dx.doi.org/10.1021/acsomega.1c00712

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