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Effect of High-Energy Milling on the Dissolution of Anti-HIV Drug Efavirenz in Different Solvents
[Image: see text] The anti-HIV drug efavirenz (EFV) displays low and variable bioavailability because of its poor aqueous solubility. Ball milling is a simple and cost-effective alternative to traditional micronization to improve the solubility and dissolution rate of EFV. A multibody dynamics model...
Autores principales: | Ataollahi, Narges, Broseghini, Marica, Ferreira, Fabio F., Susana, Alberto, Pizzato, Massimo, Scardi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154137/ https://www.ncbi.nlm.nih.gov/pubmed/34056416 http://dx.doi.org/10.1021/acsomega.1c00712 |
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