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Improved Skin Permeability after Topical Treatment with Serine Protease: Probing the Penetration of Rapamycin by Scanning Transmission X-ray Microscopy

[Image: see text] Drug penetration in human skin ex vivo following a modification of skin barrier permeability is systematically investigated by scanning transmission X-ray microscopy. Element-selective excitation is used in the O 1s regime for probing quantitatively the penetration of topically app...

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Detalles Bibliográficos
Autores principales: Germer, Gregor, Ohigashi, Takuji, Yuzawa, Hayato, Kosugi, Nobuhiro, Flesch, Roman, Rancan, Fiorenza, Vogt, Annika, Rühl, Eckart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154144/
https://www.ncbi.nlm.nih.gov/pubmed/34056375
http://dx.doi.org/10.1021/acsomega.1c01058