Cargando…

Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells

[Image: see text] Different cellular processes that contribute to protein production in Chinese hamster ovary (CHO) cells have been previously investigated by proteomics. However, although the classical secretory pathway (CSP) has been well documented as a bottleneck during recombinant protein (RP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez-Rodriguez, Saumel, Wulff, Tune, Voldborg, Bjørn G., Altamirano, Claudia, Trujillo-Roldán, Mauricio A., Valdez-Cruz, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154153/
https://www.ncbi.nlm.nih.gov/pubmed/34056395
http://dx.doi.org/10.1021/acsomega.0c06030