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A T5 Exonuclease-Based Assay for DNA Topoisomerases and DNA Intercalators

[Image: see text] DNA topoisomerases, essential enzymes to all living organisms, are important targets of certain antibiotics and anticancer drugs. Although efforts have been taken to identify new inhibitors targeting DNA topoisomerases, limited high throughput screening (HTS) studies have been cond...

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Detalles Bibliográficos
Autores principales: Deng, Zifang, Leng, Fenfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154156/
https://www.ncbi.nlm.nih.gov/pubmed/34056374
http://dx.doi.org/10.1021/acsomega.1c00962