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QM/MM Study of the Fosfomycin Resistance Mechanism Involving FosB Enzyme

[Image: see text] Multidrug-resistant organisms contain antibiotic-modifying enzymes that facilitate resistance to a variety of antimicrobial compounds. Particularly, the fosfomycin (FOF) drug can be structurally modified by several FOF-modifying enzymes before it reaches the biological target. Amon...

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Detalles Bibliográficos
Autores principales: Lima, Anderson H., Silva, José Rogério A., Alves, Cláudio Nahum, Lameira, Jerônimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154160/
https://www.ncbi.nlm.nih.gov/pubmed/34056400
http://dx.doi.org/10.1021/acsomega.1c00096