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Kynurenine Relaxes Arteries of Normotensive Women and Those With Preeclampsia

RATIONALE: Activation of the kynurenine pathway of tryptophan catabolism by infection and inflammation contributes to the development of systemic hypotension. Commercially-available kynurenine has direct vasorelaxant effects on arteries from several species and reduces systemic blood pressure when a...

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Detalles Bibliográficos
Autores principales: Worton, Stephanie A., Pritchard, Harry A.T., Greenwood, Susan L., Alakrawi, Mariam, Heazell, Alexander E.P., Wareing, Mark, Greenstein, Adam, Myers, Jenny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154175/
https://www.ncbi.nlm.nih.gov/pubmed/33656370
http://dx.doi.org/10.1161/CIRCRESAHA.120.317612