MSA-Regularized Protein Sequence Transformer toward Predicting Genome-Wide Chemical-Protein Interactions: Application to GPCRome Deorphanization

[Image: see text] Small molecules play a critical role in modulating biological systems. Knowledge of chemical–protein interactions helps address fundamental and practical questions in biology and medicine. However, with the rapid emergence of newly sequenced genes, the endogenous or surrogate ligan...

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Detalles Bibliográficos
Autores principales: Cai, Tian, Lim, Hansaim, Abbu, Kyra Alyssa, Qiu, Yue, Nussinov, Ruth, Xie, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154251/
https://www.ncbi.nlm.nih.gov/pubmed/33757283
http://dx.doi.org/10.1021/acs.jcim.0c01285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154251/
https://www.ncbi.nlm.nih.gov/pubmed/33757283
http://dx.doi.org/10.1021/acs.jcim.0c01285

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