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Protein Dynamics Influence the Enzymatic Activity of Phospholipase A/Acyltransferases 3 and 4

[Image: see text] Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity. The relation between the activity and dynamics of the N-terminal doma...

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Detalles Bibliográficos
Autores principales: Chatterjee, Soumya Deep, Zhou, Juan, Dasgupta, Rubin, Cramer-Blok, Anneloes, Timmer, Monika, van der Stelt, Mario, Ubbink, Marcellus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154263/
https://www.ncbi.nlm.nih.gov/pubmed/33749246
http://dx.doi.org/10.1021/acs.biochem.0c00974