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Structural Model for Recruitment of RIT1 to the LZTR1 E3 Ligase: Evidences from an Integrated Computational Approach

[Image: see text] Leucine-zipper transcription regulator 1 (LZTR1) is a highly mutated tumor suppressor gene, involved in the pathogenesis of several cancer types and developmental disorders. In proteasomal degradation, it acts as an adaptor protein responsible for the recognition and recruitment of...

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Detalles Bibliográficos
Autores principales: Paladino, Antonella, D’Angelo, Fulvio, Noviello, Teresa Maria Rosaria, Iavarone, Antonio, Ceccarelli, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154269/
https://www.ncbi.nlm.nih.gov/pubmed/33792302
http://dx.doi.org/10.1021/acs.jcim.1c00296