LRIG1 is a conserved EGFR regulator involved in melanoma development, survival and treatment resistance

Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a pan-negative regulator of receptor tyrosine kinase (RTK) signaling and a tumor suppressor in several cancers, but its involvement in melanoma is largely unexplored. Here, we aim to determine the role of LRIG1 in melanoma tumorigenes...

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Detalles Bibliográficos
Autores principales: Billing, Ola, Holmgren, Ylva, Nosek, Daniel, Hedman, Håkan, Hemmingsson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154585/
https://www.ncbi.nlm.nih.gov/pubmed/33947959
http://dx.doi.org/10.1038/s41388-021-01808-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154585/
https://www.ncbi.nlm.nih.gov/pubmed/33947959
http://dx.doi.org/10.1038/s41388-021-01808-3

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