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Mechanistic Differences of Activation of Rac1(P29S) and Rac1(A159V)
[Image: see text] Rac1 is a small GTPase that plays key roles in actin reorganization, cell motility, and cell survival/growth as well as in various cancer types and neurodegenerative diseases. Similar to other Ras superfamily GTPases, Rac1 switches between active GTP-bound and inactive GDP-bound st...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154616/ https://www.ncbi.nlm.nih.gov/pubmed/33848152 http://dx.doi.org/10.1021/acs.jpcb.1c00883 |