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Massively Parallel Sequencing Analysis of 68 Gastric-Type Cervical Adenocarcinomas Reveals Mutations in Cell Cycle-Related Genes and Potentially Targetable Mutations

Gastric-type cervical adenocarcinoma (GCA) is an aggressive type of endocervical adenocarcinoma characterized by mucinous morphology, gastric-type mucin, lack of association with human papillomavirus (HPV) and resistance to chemo/radiotherapy. We characterized the landscape of genetic alterations in...

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Detalles Bibliográficos
Autores principales: Selenica, Pier, Alemar, Barbara, Matrai, Cathleen, Talia, Karen L., Veras, Emanuela, Hussein, Yaser, Oliva, Esther, Beets-Tan, Regina G. H., Mikami, Yoshiki, McCluggage, W. Glenn, Kiyokawa, Takako, Weigelt, Britta, Park, Kay J., Murali, Rajmohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154628/
https://www.ncbi.nlm.nih.gov/pubmed/33318584
http://dx.doi.org/10.1038/s41379-020-00726-1