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Molecular characterization of ulcerative colitis-associated colorectal carcinomas

Patients with ulcerative colitis (UC) are at increased risk for developing colorectal cancer (CRC). In contrast to sporadic colorectal tumorigenesis, TP53 mutations occur early in the progression from inflamed colonic epithelium to dysplasia to CRC, and are sometimes readily detectable in inflamed,...

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Detalles Bibliográficos
Autores principales: Hirsch, Daniela, Hardt, Julia, Sauer, Christian, Heselmeyer-Hadded, Kerstin, Witt, Stephanie H., Kienle, Peter, Ried, Thomas, Gaiser, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8154647/
https://www.ncbi.nlm.nih.gov/pubmed/33318582
http://dx.doi.org/10.1038/s41379-020-00722-5