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Live-cell imaging reveals the spatiotemporal organization of endogenous RNA polymerase II phosphorylation at a single gene

The carboxyl-terminal domain of RNA polymerase II (RNAP2) is phosphorylated during transcription in eukaryotic cells. While residue-specific phosphorylation has been mapped with exquisite spatial resolution along the 1D genome in a population of fixed cells using immunoprecipitation-based assays, th...

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Detalles Bibliográficos
Autores principales: Forero-Quintero, Linda S., Raymond, William, Handa, Tetsuya, Saxton, Matthew N., Morisaki, Tatsuya, Kimura, Hiroshi, Bertrand, Edouard, Munsky, Brian, Stasevich, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155019/
https://www.ncbi.nlm.nih.gov/pubmed/34039974
http://dx.doi.org/10.1038/s41467-021-23417-0