NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data

The increasing availability of single-cell data revolutionizes the understanding of biological mechanisms at cellular resolution. For differential expression analysis in multi-subject single-cell data, negative binomial mixed models account for both subject-level and cell-level overdispersions, but...

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Detalles Bibliográficos
Autores principales: He, Liang, Davila-Velderrain, Jose, Sumida, Tomokazu S., Hafler, David A., Kellis, Manolis, Kulminski, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155058/
https://www.ncbi.nlm.nih.gov/pubmed/34040149
http://dx.doi.org/10.1038/s42003-021-02146-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155058/
https://www.ncbi.nlm.nih.gov/pubmed/34040149
http://dx.doi.org/10.1038/s42003-021-02146-6

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