Large red cell-derived membrane particles are major contributors to hypercoagulability in sickle cell disease

Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and resultant blood vessel blockage. Previous studies have obser...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Rachel A., Mankelow, Tosti J., Drizou, Despoina, Bullock, Thomas, Latham, Tom, Trompeter, Sara, Blair, Allison, Anstee, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155063/
https://www.ncbi.nlm.nih.gov/pubmed/34040079
http://dx.doi.org/10.1038/s41598-021-90477-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155063/
https://www.ncbi.nlm.nih.gov/pubmed/34040079
http://dx.doi.org/10.1038/s41598-021-90477-z

Ejemplares similares