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MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge

Rett syndrome is a severe and progressive neurological disorder linked to mutations in the MeCP2 gene. It has been suggested that immune alterations may play an active role in the generation and/or maintenance of RTT phenotypes. However, there is no clear consensus about which pathways are regulated...

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Detalles Bibliográficos
Autores principales: Zalosnik, M. I., Fabio, M. C., Bertoldi, M. L., Castañares, C. N., Degano, A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155097/
https://www.ncbi.nlm.nih.gov/pubmed/34040112
http://dx.doi.org/10.1038/s41598-021-90517-8