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Optimised GMP-compliant production of [(18)F]DPA-714 on the Trasis AllinOne module
BACKGROUND: The translocator protein 18 kDa is recognised as an important biomarker for neuroinflammation due to its soaring expression in microglia. This process is common for various neurological disorders. DPA-714 is a potent TSPO-specific ligand which found its use in Positron Emission Tomograph...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155128/ https://www.ncbi.nlm.nih.gov/pubmed/34037896 http://dx.doi.org/10.1186/s41181-021-00133-0 |