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Optimised GMP-compliant production of [(18)F]DPA-714 on the Trasis AllinOne module

BACKGROUND: The translocator protein 18 kDa is recognised as an important biomarker for neuroinflammation due to its soaring expression in microglia. This process is common for various neurological disorders. DPA-714 is a potent TSPO-specific ligand which found its use in Positron Emission Tomograph...

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Detalles Bibliográficos
Autores principales: Cybulska, Klaudia A., Bloemers, Vera, Perk, Lars R., Laverman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155128/
https://www.ncbi.nlm.nih.gov/pubmed/34037896
http://dx.doi.org/10.1186/s41181-021-00133-0