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Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells

Compact cardiomyocytes that make up the ventricular wall of the adult heart represent an important therapeutic target population for modeling and treating cardiovascular diseases. Here, we established a differentiation strategy that promotes the specification, proliferation and maturation of compact...

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Detalles Bibliográficos
Autores principales: Funakoshi, Shunsuke, Fernandes, Ian, Mastikhina, Olya, Wilkinson, Dan, Tran, Thinh, Dhahri, Wahiba, Mazine, Amine, Yang, Donghe, Burnett, Benjamin, Lee, Jeehoon, Protze, Stephanie, Bader, Gary D., Nunes, Sara S., Laflamme, Michael, Keller, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155185/
https://www.ncbi.nlm.nih.gov/pubmed/34039977
http://dx.doi.org/10.1038/s41467-021-23329-z