The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

RNA splicing, transcription and the DNA damage response are intriguingly linked in mammals but the underlying mechanisms remain poorly understood. Using an in vivo biotinylation tagging approach in mice, we show that the splicing factor XAB2 interacts with the core spliceosome and that it binds to s...

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Detalles Bibliográficos
Autores principales: Goulielmaki, Evi, Tsekrekou, Maria, Batsiotos, Nikos, Ascensão-Ferreira, Mariana, Ledaki, Eleftheria, Stratigi, Kalliopi, Chatzinikolaou, Georgia, Topalis, Pantelis, Kosteas, Theodore, Altmüller, Janine, Demmers, Jeroen A., Barbosa-Morais, Nuno L., Garinis, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155215/
https://www.ncbi.nlm.nih.gov/pubmed/34039990
http://dx.doi.org/10.1038/s41467-021-23505-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155215/
https://www.ncbi.nlm.nih.gov/pubmed/34039990
http://dx.doi.org/10.1038/s41467-021-23505-1

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