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The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing
RNA splicing, transcription and the DNA damage response are intriguingly linked in mammals but the underlying mechanisms remain poorly understood. Using an in vivo biotinylation tagging approach in mice, we show that the splicing factor XAB2 interacts with the core spliceosome and that it binds to s...
Autores principales: | Goulielmaki, Evi, Tsekrekou, Maria, Batsiotos, Nikos, Ascensão-Ferreira, Mariana, Ledaki, Eleftheria, Stratigi, Kalliopi, Chatzinikolaou, Georgia, Topalis, Pantelis, Kosteas, Theodore, Altmüller, Janine, Demmers, Jeroen A., Barbosa-Morais, Nuno L., Garinis, George A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155215/ https://www.ncbi.nlm.nih.gov/pubmed/34039990 http://dx.doi.org/10.1038/s41467-021-23505-1 |
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