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Longitudinal Assessment of Working Memory Performance in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease Using an Automated Figure-8-Maze

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, with a long preclinical and prodromal phase. To enable the study of disease mechanisms, AD has been modeled in many transgenic animal lines and cognitive functioning has been tested using several widely used behavioral tasks. Thes...

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Detalles Bibliográficos
Autores principales: van Heusden, Fran C., Palacín i Bonsón, Sara, Stiedl, Oliver, Smit, August B., van Kesteren, Ronald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155296/
https://www.ncbi.nlm.nih.gov/pubmed/34054444
http://dx.doi.org/10.3389/fnbeh.2021.655449