Cargando…

Enamine N-Oxides: Synthesis and Application to Hypoxia-Responsive Prodrugs and Imaging Agents

[Image: see text] Tumor hypoxia induces the large-scale adaptive reprogramming of cancer cells, promoting their transformation into highly invasive and metastatic species that lead to highly negative prognoses for cancer patients. We describe the synthesis and application of a hypoxia-responsive tri...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Dahye, Cheung, Sheldon T., Wong-Rolle, Andrew, Kim, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155465/
https://www.ncbi.nlm.nih.gov/pubmed/34056093
http://dx.doi.org/10.1021/acscentsci.0c01586