Cargando…

Computational Modeling for Antiarrhythmic Drugs for Atrial Fibrillation According to Genotype

Background: The efficacy of antiarrhythmic drugs (AAD) can vary in patients with atrial fibrillation (AF), and the PITX2 gene affects the responsiveness of AADs. We explored the virtual AAD (V-AAD) responses between wild-type and PITX2(+/−)-deficient AF conditions by realistic in silico AF modeling....

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Inseok, Jin, Ze, Park, Je-Wook, Kwon, Oh-Seok, Lim, Byounghyun, Hong, Myunghee, Kim, Min, Yu, Hee-Tae, Kim, Tae-Hoon, Uhm, Jae-Sun, Joung, Boyoung, Lee, Moon-Hyoung, Pak, Hui-Nam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155488/
https://www.ncbi.nlm.nih.gov/pubmed/34054570
http://dx.doi.org/10.3389/fphys.2021.650449