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Computational Modeling for Antiarrhythmic Drugs for Atrial Fibrillation According to Genotype
Background: The efficacy of antiarrhythmic drugs (AAD) can vary in patients with atrial fibrillation (AF), and the PITX2 gene affects the responsiveness of AADs. We explored the virtual AAD (V-AAD) responses between wild-type and PITX2(+/−)-deficient AF conditions by realistic in silico AF modeling....
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155488/ https://www.ncbi.nlm.nih.gov/pubmed/34054570 http://dx.doi.org/10.3389/fphys.2021.650449 |