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Computational Modeling for Antiarrhythmic Drugs for Atrial Fibrillation According to Genotype

Background: The efficacy of antiarrhythmic drugs (AAD) can vary in patients with atrial fibrillation (AF), and the PITX2 gene affects the responsiveness of AADs. We explored the virtual AAD (V-AAD) responses between wild-type and PITX2(+/−)-deficient AF conditions by realistic in silico AF modeling....

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Detalles Bibliográficos
Autores principales:	Hwang, Inseok, Jin, Ze, Park, Je-Wook, Kwon, Oh-Seok, Lim, Byounghyun, Hong, Myunghee, Kim, Min, Yu, Hee-Tae, Kim, Tae-Hoon, Uhm, Jae-Sun, Joung, Boyoung, Lee, Moon-Hyoung, Pak, Hui-Nam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155488/ https://www.ncbi.nlm.nih.gov/pubmed/34054570 http://dx.doi.org/10.3389/fphys.2021.650449

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