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Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling

Objectives: Natural product, osthole, has been proven to have a protective effect on organ fibrosis, including renal fibrosis. All of these studies are mainly focused on the regulation of TGF-β/Smad signaling pathway. However, due to the pleiotropic roles of TGF-β/Smad signaling, direct TGF-β-target...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Zhao, Yan, Shao, Qingqing, Fang, Ke, Dong, Ruolan, Jiang, Shujun, Lu, Fuer, Luo, Jinlong, Chen, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155534/
https://www.ncbi.nlm.nih.gov/pubmed/34054526
http://dx.doi.org/10.3389/fphar.2021.646331