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Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling
Objectives: Natural product, osthole, has been proven to have a protective effect on organ fibrosis, including renal fibrosis. All of these studies are mainly focused on the regulation of TGF-β/Smad signaling pathway. However, due to the pleiotropic roles of TGF-β/Smad signaling, direct TGF-β-target...
Autores principales: | Wu, Fan, Zhao, Yan, Shao, Qingqing, Fang, Ke, Dong, Ruolan, Jiang, Shujun, Lu, Fuer, Luo, Jinlong, Chen, Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155534/ https://www.ncbi.nlm.nih.gov/pubmed/34054526 http://dx.doi.org/10.3389/fphar.2021.646331 |
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