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Energy Starvation Induces a Cell Cycle Arrest in Escherichia coli by Triggering Degradation of the DnaA Initiator Protein

During steady-state Escherichia coli growth, the amount and activity of the initiator protein, DnaA, controls chromosome replication tightly so that initiation only takes place once per origin in each cell cycle, regardless of growth conditions. However, little is known about the mechanisms involved...

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Detalles Bibliográficos
Autores principales: Charbon, Godefroid, Mendoza-Chamizo, Belén, Campion, Christopher, Li, Xiaobo, Jensen, Peter Ruhdal, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155583/
https://www.ncbi.nlm.nih.gov/pubmed/34055872
http://dx.doi.org/10.3389/fmolb.2021.629953