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Opportunities and Challenges in Global Quantification of RNA-Protein Interaction via UV Cross-Linking

RNA-binding proteins (RBPs) are key mediators of posttranscriptional gene expression control. However, the links between cell signaling on the one hand and RBP function on the other are understudied. While thousands of posttranslational modification (PTM) sites on RBPs have been identified, their fu...

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Detalles Bibliográficos
Autores principales: Vieira-Vieira, Carlos H., Selbach, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155585/
https://www.ncbi.nlm.nih.gov/pubmed/34055886
http://dx.doi.org/10.3389/fmolb.2021.669939