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Maternal-Fetal HLA Compatibility in Uncomplicated and Preeclamptic Naturally Conceived Pregnancies

INTRODUCTION: In pregnancy, the mother and fetus differ in HLA antigens, and yet the maternal immune system generally tolerates the fetus. KIR receptors expressed by maternal uterine NK cells at the maternal-fetal interface directly interact with HLA-C on extravillous trophoblast cells for optimal p...

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Detalles Bibliográficos
Autores principales: van ‘t Hof, Liseanne J., Schotvanger, Naomi, Haasnoot, Geert W., van der Keur, Carin, Roelen, Dave L., Lashley, Lisa E. E. L. O., Claas, Frans H. J., Eikmans, Michael, van der Hoorn, Marie-Louise P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155594/
https://www.ncbi.nlm.nih.gov/pubmed/34054856
http://dx.doi.org/10.3389/fimmu.2021.673131