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Antibodies Against Angiotensin II Receptor Type 1 and Endothelin A Receptor Are Associated With an Unfavorable COVID19 Disease Course

BACKGROUND: Lung histopathology demonstrates vasculopathy in a subset of deceased COVID19 patients, which resembles histopathology observed in antibody-mediated lung transplant rejection. Autoantibodies against angiotensin II type 1 receptor (AT1R) and Endothelin receptor Type A (ETAR) have been dem...

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Detalles Bibliográficos
Autores principales: Miedema, Jelle, Schreurs, Marco, van der Sar – van der Brugge, Simone, Paats, Marthe, Baart, Sara, Bakker, Marleen, Hoek, Rogier, Dik, Willem Arnout, Endeman, Henrik, Van Der Velden, Vincent, van Gammeren, Adriaan, Ermens, Antonius, Aerts, Joachim G., Thüsen, Jan Von Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155664/
https://www.ncbi.nlm.nih.gov/pubmed/34054876
http://dx.doi.org/10.3389/fimmu.2021.684142