Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development

The developing retina expresses multiple bHLH transcription factors. Their precise functions and interactions in uncommitted retinal progenitors remain to be fully elucidated. Here, we investigate the roles of bHLH factors ATOH7 and Neurog2 in human ES cell-derived retinal organoids. Single cell tra...

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Detalles Bibliográficos
Autores principales: Zhang, Xiangmei, Mandric, Igor, Nguyen, Kevin H., Nguyen, Thao T. T., Pellegrini, Matteo, Grove, James C. R., Barnes, Steven, Yang, Xian-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155690/
https://www.ncbi.nlm.nih.gov/pubmed/34055784
http://dx.doi.org/10.3389/fcell.2021.653305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155690/
https://www.ncbi.nlm.nih.gov/pubmed/34055784
http://dx.doi.org/10.3389/fcell.2021.653305

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