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Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development
The developing retina expresses multiple bHLH transcription factors. Their precise functions and interactions in uncommitted retinal progenitors remain to be fully elucidated. Here, we investigate the roles of bHLH factors ATOH7 and Neurog2 in human ES cell-derived retinal organoids. Single cell tra...
Autores principales: | Zhang, Xiangmei, Mandric, Igor, Nguyen, Kevin H., Nguyen, Thao T. T., Pellegrini, Matteo, Grove, James C. R., Barnes, Steven, Yang, Xian-Jie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155690/ https://www.ncbi.nlm.nih.gov/pubmed/34055784 http://dx.doi.org/10.3389/fcell.2021.653305 |
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