Acute acetate administration increases endogenous opioid levels in the human brain: A [(11)C]carfentanil molecular imaging study

INTRODUCTION: A recent study has shown that acetate administration leads to a fourfold increase in the transcription of proopiomelanocortin (POMC) mRNA in the hypothalamus. POMC is cleaved to peptides, including β-endorphin, an endogenous opioid (EO) agonist that binds preferentially to the µ-opioid...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashok, Abhishekh H, Myers, Jim, Frost, Gary, Turton, Samuel, Gunn, Roger N, Passchier, Jan, Colasanti, Alessandro, Marques, Tiago Reis, Nutt, David, Lingford-Hughes, Anne, Howes, Oliver D, Rabiner, Eugenii A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155733/
https://www.ncbi.nlm.nih.gov/pubmed/33406950
http://dx.doi.org/10.1177/0269881120965912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155733/
https://www.ncbi.nlm.nih.gov/pubmed/33406950
http://dx.doi.org/10.1177/0269881120965912

Ejemplares similares