Mechanism of p38 MAPK–induced EGFR endocytosis and its crosstalk with ligand-induced pathways

Ligand binding triggers clathrin-mediated and, at high ligand concentrations, clathrin-independent endocytosis of EGFR. Clathrin-mediated endocytosis (CME) of EGFR is also induced by stimuli activating p38 MAPK. Mechanisms of both ligand- and p38-induced endocytosis are not fully understood, and how...

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Detalles Bibliográficos
Autores principales: Perez Verdaguer, Mireia, Zhang, Tian, Paulo, Joao A., Gygi, Steven, Watkins, Simon C., Sakurai, Hiroaki, Sorkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155814/
https://www.ncbi.nlm.nih.gov/pubmed/34032851
http://dx.doi.org/10.1083/jcb.202102005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155814/
https://www.ncbi.nlm.nih.gov/pubmed/34032851
http://dx.doi.org/10.1083/jcb.202102005

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