Preconditioning or Postconditioning with 8-Br-cAMP-AM Protects the Heart against Regional Ischemia and Reperfusion: A Role for Mitochondrial Permeability Transition

The cAMP analogue 8-Br-cAMP-AM (8-Br) confers marked protection against global ischaemia/reperfusion of isolated perfused heart. We tested the hypothesis that 8-Br is also protective under clinically relevant conditions (regional ischaemia) when applied either before ischemia or at the beginning of...

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Detalles Bibliográficos
Autores principales: Khaliulin, Igor, Ascione, Raimondo, Maslov, Leonid N., Amal, Haitham, Suleiman, M. Saadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155893/
https://www.ncbi.nlm.nih.gov/pubmed/34067674
http://dx.doi.org/10.3390/cells10051223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155893/
https://www.ncbi.nlm.nih.gov/pubmed/34067674
http://dx.doi.org/10.3390/cells10051223

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