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Cyclodextrin Inclusion Complexes of Auranofin and Its Iodido Analog: A Chemical and Biological Study

Auranofin (AF) and its iodido analog, i.e., Au(PEt(3)) I (AFI), were reported to exhibit very promising anticancer properties both in vitro and in vivo. However, both these gold compounds have a scarce aqueous solubility that hampers their pharmaceutical use. Here, we explore whether encapsulation o...

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Detalles Bibliográficos
Autores principales: Cirri, Damiano, Landini, Ida, Massai, Lara, Mini, Enrico, Maestrelli, Francesca, Messori, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155929/
https://www.ncbi.nlm.nih.gov/pubmed/34063389
http://dx.doi.org/10.3390/pharmaceutics13050727