Double p52Shc/p46Shc Rat Knockout Demonstrates Severe Gait Abnormalities Accompanied by Dilated Cardiomyopathy

The ubiquitously expressed adaptor protein Shc exists in three isoforms p46Shc, p52Shc, and p66Shc, which execute distinctly different actions in cells. The role of p46Shc is insufficiently studied, and the purpose of this study was to further investigate its functional significance. We developed un...

Descripción completa

Detalles Bibliográficos
Autores principales: Miller, Bradley, Kostrominova, Tatiana Y., Geurts, Aron M., Sorokin, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155973/
https://www.ncbi.nlm.nih.gov/pubmed/34063460
http://dx.doi.org/10.3390/ijms22105237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8155973/
https://www.ncbi.nlm.nih.gov/pubmed/34063460
http://dx.doi.org/10.3390/ijms22105237

Ejemplares similares