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Gemini Cationic Lipid-Type Nanovectors Suitable for the Transfection of Therapeutic Plasmid DNA Encoding for Pro-Inflammatory Cytokine Interleukin-12

Ample evidence exists on the role of interleukin-12 (IL-12) in the response against many pathogens, as well as on its remarkable antitumor properties. However, the unexpected toxicity and disappointing results in some clinical trials are prompting the design of new strategies and/or vectors for IL-1...

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Detalles Bibliográficos
Autores principales: Sánchez-Arribas, Natalia, Martínez-Negro, María, Aicart-Ramos, Clara, Tros de Ilarduya, Conchita, Aicart, Emilio, Guerrero-Martínez, Andrés, Junquera, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156092/
https://www.ncbi.nlm.nih.gov/pubmed/34063469
http://dx.doi.org/10.3390/pharmaceutics13050729