Inter- and Intra-Molecular Organocatalysis of S(N)2 Fluorination by Crown Ether: Kinetics and Quantum Chemical Analysis

We present the intra- and inter-molecular organocatalysis of S(N)2 fluorination using CsF by crown ether to estimate the efficacy of the promoter and to elucidate the reaction mechanism. The yields of intramolecular S(N)2 fluorination of the veratrole substrates are measured to be very small (<1%...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Young-Ho, Yun, Wonhyuck, Kim, Chul-Hee, Jang, Sung-Woo, Lee, Sung-Sik, Lee, Sungyul, Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156096/
https://www.ncbi.nlm.nih.gov/pubmed/34063489
http://dx.doi.org/10.3390/molecules26102947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156096/
https://www.ncbi.nlm.nih.gov/pubmed/34063489
http://dx.doi.org/10.3390/molecules26102947

Ejemplares similares